Western blot test lyme accuracy2/6/2024 ![]() Alternatively, the polymerase chain reaction (PCR) is a highly sensitive test that detects DNA from the Borrelia bacteria in fluid drawn from an infected joint (typically synovial or cerebrospinal fluid).Together these tests are known as the ELISA/Western Blot. The Western blot detects antibodies to several proteins of B. The western blot is usually run as a second-stage to confirm the diagnosis following a positive ELISA result.burgdorferi and, if positive, is followed up by the Western Blot test. The Enzyme-linked immunosorbent assay or ELISA is the first step.The following tests are FDA-approved for diagnosis: There is much debate over the accuracy and reliability of the laboratory tests and the likelihood of false positives and false negatives. ![]() Lyme disease is typically assessed based on clinical diagnosis, in combination with laboratory tests. What does this mean for you? By all means, if your doctor recommends a test, get the test. In other words you could have Lyme but the test results will still come up negative. It can take your body up to two months to develop enough antibodies to be detected by these tests. Therefore a blood test at this time will often appear negative. However, with early-stage Lyme your antibodies may not have had time to develop in your body. This bacteria is called Borrelia burgdorferi, or Bb. The current laboratory diagnostic tests for Lyme disease are blood tests to detect the antibodies created by your body to fight and kill the bacteria that causes Lyme.
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